Thirty-two male rats were trained to self-administer methamphetamine by pressing a lever during two hour sessions until they were addicted. The rats were then split into two groups: the first group of rats were systematically given CBD based on how often they were seeking out the methamphetamine; the second group of rats were treated with CBD only and their behavior was monitored.
CBD reduced the motivation to self-administer methamphetamine and lessened the relapse of methamphetamine-seeking behaviors. The researchers determined that CBD can reduce the motivation to seek out methamphetamine during addiction and post-addiction. The researchers also concluded that their study was the first demonstration “that cannabidiol can reduce the motivation to seek and consume methamphetamine, and suggests that cannabidiol might be worth trialing as a novel pharmacotherapy for methamphetamine dependence.” To read the original research article, please see the link here.