Cannabidiol has demonstrated, in studies, to have antiepileptic properties and has had widespread success as a treatment therapy for various types of seizure disorders.
CBD was shown to elevate levels of anandamide, resulting in anti-inflammatory and anti-allergenic properties.
The study confirmed that CBD was successfully able to control RBD symptoms in Parkinson’s patients and was published in the Journal of Clinical Pharmacy and Therapeutics.
Sullivan University College of Pharmacy in Louisville, Kentucky, researched the effects of CBD therapy on ovarian cancer cells.
In a study performed by the Department of Pharmacology and Toxicology at the Medical College of Georgia, researchers studied the protective effects of cannabidiol (CBD) on rats with diabetic retinopathy.
CBD treatment effectively decreased her anxiety and she showed steady improvement of both sleep duration and quality.
The study clearly demonstrated the cardioprotective properties of CBD in the acute phase of I/R injuries due to the fact it both reduced ventricular arrhythmias and reduced infarct sizes.
Preliminary research has shown CBD to be an effective, targeted and non-toxic option that could regulate the metastatic properties of breast and other cancers.
In an effort find new treatment therapies for breast cancer, researchers have begun to study cannabidiol, or CBD. Cannabidiol is one of the major non-psychoactive components of the hemp plant. CBD has become increasingly popular to treat a wide variety of ailments do to its ability to regulate the body’s endocannabinoid system. Preliminary research has shown CBD to be an effective, targeted and non-toxic option that could regulate the metastatic properties of breast and other cancers.
At the California Pacific Medical Center in San Francisco, California, researchers had previously reported that cannabidiol exhibits a very low toxicity profile and effectively down-regulates the Id-1 gene expression in breast cancer cells in cultures. Their continued research has shown that the down-regulation of Id-1 by CBD also inhibits the proliferative and invasive phenotype of breast cancer cells. Their studies have also shown that CBD therapy effectively reduces the primary tumor mass, as well as, the size and frequency of metastases in mice.
The important research being done at the California Pacific Medical Center further proves how significant CBD could be to the medical community. We eagerly await further studies demonstrating the effects cannabidiol has on cancer cells.
To read more about the study referenced above, please see here.
Neuroscientists conducted a study to examine the potential effects of cannabidiol on the PI3K/AKT/m/TOR pathway.
Multiple Sclerosis, or MS, is a chronic disease in which damage occurs to the sheaths of nerve cells in the brain and spinal cord. Often a progressive disease, symptoms can include pain, numbness, speech impairment and fatigue. Researchers have begun to study cannabidiol (CBD) as a possible treatment therapy, as CBD is one of the many compounds found in hemp and has a diverse pharmacological profile with little to no adverse side effects.
The PI3K/AKT/m/TOR pathway, an intracellular signaling pathway which regulates cell cycles, has become of interest to researchers studying MS, as it plays a major part in cellular quiescence, proliferation, cancer and longevity. Neuroscientists at the Contrada Casazza, in Italy, conducted a study in 2017 to examine the potential effects of cannabidiol on the PI3K/AKT/m/TOR pathway.
In their study, researchers induced mice with the most common model of MS. After the disease symptoms began, the mice were treated with CBD at a rate of 10mg/kg of body weight daily and observed for clinical signs of MS. After 28 days, the mice were euthanized and spinal tissues were sampled. The results demonstrated a clear downregulation of the PI3K/AKT/m/TOR pathway and that CBD was effectively able to restore it. Their data demonstrated the therapeutic efficacy of CBD, due to the reduction of pro-inflammatory cytokines and the promotion of cell neuron survival. They concluded their study by stating that the, “results provide an interesting discovery about the regulation of the PI3K/AKT/m/TOR pathway by cannabidiol administration, that could be a new potential therapeutic target for MS management.”
This is exciting news for Multiple Sclerosis patients. We hope research will continue to investigate how CBD can regulate the PI3K/AKT/m/TOR pathway and how it could benefit those suffering from MS. To learn more about the study referenced above, click here.
This study recognizes the important role of CBD in treating neonatal HI injuries, in addition to, protecting newborns from long-term brain damage.
When babies are born unable to breathe properly, they can develop hypoxia-ischemia (HI), a condition which occurs when the brain doesn’t receive enough oxygen. HI may cause long-term side effects, including brain damage, of varying severity. With limited treatment options available to premature newborn and babies, researchers have been searching for an effective method to protect delicate brain cells. Cannabidiol (CBD), a non-psychoactive cannabinoid, or chemical component of the hemp plant, has previously demonstrated short-term neuroprotective properties on the brain, following a HI injury, during clinical studies.
As a follow-up to previous studies, researchers at the Foundation for Biomedical Research in Madrid, Spain, examined the neuroprotective effects of CBD and if those effects were sustainable long-term. Newborn rats sustained a HI injury, with some receiving CBD treatment alongside non-treated rats. After 30 days, the rats were subjected to magnetic resonance imaging, histological evaluation, magnetic resonance spectroscopy and Western blotting to evaluate whether the CBD treatments had any lasting effects on the brain tissue. Their results showed that CBD effectively modulated brain excitotoxicity, oxidative stress and inflammation. This study recognizes the important role of CBD in treating neonatal HI injuries, in addition to, protecting newborns from long-term brain damage.
To read more about the aforementioned study, please click here.